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What is Learnable in Valiant's Theory of the Learnable? Learning Perturbations to Extrapolate Your LLM Byzantine-Robust Distributed Sparse Learning Revisited The Sample Complexity of Multiple Change Point Identification under Bandit Feedback A proximal gradient algorithm for composite log-concave sampling Model-based Bootstrap of Controlled Markov Chains Approximation of Maximally Monotone Operators : A Graph Convergence Perspective Posterior Contraction Rates for Sparse Kolmogorov-Arnold Networks in Anisotropic Besov Spaces MIST: Reliable Streaming Decision Trees for Online Class-Incremental Learning via McDiarmid Bound A Spectral Framework for Closed-Form Relative Density Estimation Fast Rates for Offline Contextual Bandits with Forward-KL Regularization under Single-Policy Concentrability Higher-Order Equilibrium Tracking for EM-Compressible Online Estimation Scaling Limits of Long-Context Transformers A Note on Non-Negative $L_1$-Approximating Polynomials Susceptibilities and Patterning: A Primer on Linear Response in Bayesian Learning Linear Response Estimators for Singular Statistical Models Statistical inference with belief functions: A survey Robust stochastic first order methods in heavy-tailed noise via medoid mini-batch gradient sampling Every Feedforward Neural Network Definable in an o-Minimal Structure Has Finite Sample Complexity Adaptive auditing of AI systems with anytime-valid guarantees Locally Near Optimal Piecewise Linear Regression in High Dimensions via Difference of Max-Affine Functions Risk-Controlled Post-Processing of Decision Policies Covariate Balancing and Riesz Regression Should Be Guided by the Neyman Orthogonal Score in Debiased Machine Learning A Unified Pair-GRPO Family: From Implicit to Explicit Preference Constraints for Stable and General RL Alignment Time-Inhomogeneous Preconditioned Langevin Dynamics A Fine-Grained Understanding of Uniform Convergence for Halfspaces CITE: Anytime-Valid Statistical Inference in LLM Self-Consistency Ratio-based Loss Functions Optimal Confidence Band for Kernel Gradient Flow Estimator A renormalization-group inspired lattice-based framework for piecewise generalized linear models
Application of the fractional stable distributions for ap...
Viacheslav Saenko, Yurij Saenko · 2014-06-27 · via math.ST updates on arXiv.org

At the present time reliably established that probability density functions of gene expression of microarray experiments possess a number of universal properties. First of all these distributions have power asymptotic and secondly the shape of these distributions are inherent for all organisms and tissues. This fact led to appearance of a number works where authors are investigating various probability distributions for approximation of empirical distributions of gene expression. Nevertheless all these distributions aren't limit distribution and aren't solution of any equations. These facts by our opinion are essential shortcoming of these probability laws. Besides, expression of individual gene aren't accidental event and it depends from expression other genes. This allows to talk about existence of genic regulatory net in the cell. In the work the class of fractional stable distributions (FSD) are described. This class of distributions is limit distribution of sum independent identical distributed random variables. These distributions have power-law asymptotic and this fact allow us to apply their for approximation of experimental densities gene expression of microarray experiments. The parameters of FSDs are statistically estimated by experimental dates and empirical density is compared whit theoretical density. In the work the algorithms of parameters estimation and simulating of FSD variables are presented. The results of such comparison allow to make conclusion that empirical densities of gene expression can be approximate by FSD.