In contrast to parametric spectrum sensing, non-parametric spectrum sensing can effectively detect the primary user's presence or absence without prior information about the primary user. Particularly, non-parametric spectrum sensing can be useful in dynamic spectrum sharing. The secondary user must detect incumbents and peer secondary users in dynamic spectrum sharing. The secondary user can use the licensed spectrum if the primary user is not detected using its band. The primary user detection problem is the goodness-of-fit testing problem. In this work, we performed a hardware-in-the-loop evaluation of goodness-of-fit tests such as Cramer-von-Mises (CM), Anderson-Darling (AD) and Kolmogorov-Smirnov (KS) tests. We used a wideband radio transceiver RFSoC 4x2 from AMD and an F8 radio channel emulator to perform GoF tests.