We study the problem of estimating the source of a network cascade given a time series of noisy information about the spread. Initially, there is a single vertex affected by the cascade (the source) and the cascade spreads in discrete time steps across the network. The cascade evolution is hidden, but one can observe a time series of noisy signals from each vertex. The time series of a vertex is assumed to be a sequence of i.i.d. samples from a pre-change distribution $Q_0$ before the cascade affects the vertex, and the time series is a sequence of i.i.d. samples from a post-change distribution $Q_1$ once the cascade has affected the vertex. Given the time series of noisy signals, which can be viewed as a noisy measurement of the cascade evolution, we aim to devise a procedure to reliably estimate the cascade source as fast as possible. We investigate Bayesian and minimax formulations of the source estimation problem, and derive near-optimal estimators for simple cascade dynamics and network topologies. In the Bayesian setting, an estimator which observes samples until the error of the Bayes-optimal estimator falls below a threshold achieves optimal performance. In the minimax setting, optimal performance is achieved by designing a novel multi-hypothesis sequential probability ratio test (MSPRT). We find that these optimal estimators require $\log \log n / \log (k - 1)$ observations of the noisy time series when the network topology is a $k$-regular tree, and $(\log n)^{\frac{1}{\ell + 1}}$ observations are required for $\ell$-dimensional lattices. Finally, we discuss how our methods may be extended to cascades on arbitrary graphs.