We consider semiparametric transformation models, where after pre-estimation of a parametric transformation of the response the data are modeled by means of nonparametric regression. We suggest subsequent procedures for testing lack-of-fit of the regression function and for significance of covariables, which - in contrast to procedures from the literature - are asymptotically not influenced by the pre-estimation of the transformation. The test statistics are asymptotically pivotal and have the same asymptotic distribution as in regression models without transformation. We show validity of a multiplier bootstrap procedure which is easier to implement and much less computationally demanding than bootstrap procedures based on the transformation model. In a simulation study we demonstrate the superior performance of the procedure in comparison with the competitors from the literature.