We study the problem of high-dimensional covariance estimation under the constraint that the partial correlations are nonnegative. The sign constraints dramatically simplify estimation: the Gaussian maximum likelihood estimator is well defined with only two observations regardless of the number of variables. We analyze its performance in the setting where the dimension may be much larger than the sample size. We establish that the estimator is both high-dimensionally consistent and minimax optimal in the symmetrized Stein loss. We also prove a negative result which shows that the sign-constraints can introduce substantial bias for estimating the top eigenvalue of the covariance matrix.