We introduce an extension of the Difference of Convex Algorithm (DCA) in the form of a randomized block coordinate approach for problems with separable structure. For $n$ coordinate-blocks and $k$ iterations, our main result proves a non-asymptotic convergence rate of $O(n/k)$ in expectation, with respect to a stationarity measure based on a Forward-Backward envelope. Furthermore, leveraging the connection between DCA and Expectation Maximization (EM), we propose a randomized block coordinate EM algorithm.