We focus on fast-slow systems involving both fractional Brownian motion (fBm) and standard Brownian motion (Bm). The integral with respect to Bm is the standard Ito integral, and the integral with respect to fBm is the generalised Riemann-Stieltjes integral using the tools of fractional calculus. An averaging principle in which the fast-varying diffusion process of the fast-slow systems acts as a noise to be averaged out in the limit is established. It is shown that the slow process has a limit in the mean square sense, which is characterized by the solution of stochastic differential equations driven by fBm whose coefficients are averaged with respect to the stationary measure of the fast-varying diffusion. The implication is that one can ignore the complex original systems and concentrate on the averaged systems instead. This averaging principle paves the way for reduction of computational complexity.