Consider non-linear time-fractional stochastic reaction-diffusion equations of the following type, $$\partial^β_tu_t(x)=-ν(-Δ)^{α/2} u_t(x)+I^{1-β}_t[b(u)+ σ(u)\stackrel{\cdot}{F}(t,x)]$$ in $(d+1)$ dimensions, where $ν>0, β\in (0,1)$, $α\in (0,2]$. The operator $\partial^β_t$ is the Caputo fractional derivative while $-(-Δ)^{α/2} $ is the generator of an isotropic $α$-stable Lévy process and $I^{1-β}_t$ is the Riesz fractional integral operator. The forcing noise denoted by $\stackrel{\cdot}{F}(t,x)$ is a Gaussian noise. These equations might be used as a model for materials with random thermal memory. We derive non-existence (blow-up) of global random field solutions under some additional conditions, most notably on $b$, $σ$ and the initial condition. Our results complement those of P. Chow in \cite{chow2}, \cite{chow1}, and Foondun et al. in \cite{Foondun-liu-nane}, \cite{foondun-parshad} among others.