In this work we provide explicit conditions on the existence of optimal feedback controls for stochastic processes with regime-switching. We use the compactification method which needs less regularity conditions on the coefficients of the studied stochastic systems. Two different kinds of controls have been considered: one is the control on the coefficients of the diffusion processes, another is the control on the transition rate matrices of the continuous-time Markov chains. Moreover, the dynamic programming principle is established after showing the continuity of the value function.