Sharp conditions for the presence of spectral outliers are well understood for Wigner random matrices with iid entries. In the setting of inhomogeneous symmetric random matrices (i.e., matrices with a non-trivial variance profile), the corresponding problem has been considered only recently. Of special interest is the setting of sparse inhomogeneous matrices since sparsity is both a key feature and a technical obstacle in various aspects of random matrix theory. For such matrices, the largest of the variances of the entries has been used in the literature as a natural proxy for sparsity. We contribute sharp conditions in terms of this parameter for an inhomogeneous symmetric matrix with sub-Gaussian entries to have outliers. Our result implies a ``structural'' universality principle: the presence of outliers is only determined by the level of sparsity, rather than the detailed structure of the variance profile.