Building on the work of Arizmendi and Celestino (2021), we derive the $*$-distributions of polynomials in monotone independent and infinitesimally monotone independent elements. For non-zero complex numbers $α$ and $β$, we derive explicitly the $*$-distribution of $p_{α,β}=αab + βba$ whenever $a$ and $b$ are monotone or infinitesimally monotone independent elements. This encompasses both cases of the commutator and anti-commutator. This approach can be pushed to study more general polynomials. As applications, we derive the limiting distribution with respect to the partial trace of polynomials in a certain class of random matrices.