We study the problem of sampling from a target distribution $π(q)\propto e^{-U(q)}$ on $\mathbb{R}^d$, where $U$ can be non-convex, via the Hessian-free high-resolution (HFHR) dynamics, which is a second-order Langevin-type process that has $e^{-U(q)-\frac12|p|^2}$ as its unique invariant distribution, and it reduces to kinetic Langevin dynamics (KLD) as the resolution parameter $α\to0$. The existing theory for HFHR dynamics in the literature is restricted to strongly-convex $U$, although numerical experiments are promising for non-convex settings as well. We focus on studying the convergence of HFHR dynamics when $U$ can be non-convex, which bridges a gap between theory and practice. Under a standard assumption of dissipativity and smoothness on $U$, we adopt the reflection/synchronous coupling method. This yields a Lyapunov-weighted Wasserstein distance in which the HFHR semigroup is exponentially contractive for all sufficiently small $α>0$ whenever KLD is. We further show that, under an additional assumption that asymptotically $\nabla U$ has linear growth at infinity, the contraction rate for HFHR dynamics is strictly better than that of KLD, with an explicit gain. As a case study, we verify the assumptions and the resulting acceleration for three examples: a multi-well potential, Bayesian linear regression with $L^p$ regularizer and Bayesian binary classification. We conduct numerical experiments based on these examples, as well as an additional example of Bayesian logistic regression with real data processed by the neural networks, which illustrates the efficiency of the algorithms based on HFHR dynamics and verifies the acceleration and superior performance compared to KLD.