In this work we investigate how quantum expanders (i.e. quantum channels with few Kraus operators but a large spectral gap) can be constructed from unitary designs. Concretely, we prove that a random quantum channel whose Kraus operators are independent unitaries sampled from a $2$-design measure is with high probability an optimal expander (in the sense that its spectral gap is as large as possible). More generally, we show that, if these Kraus operators are independent unitaries of the form $U^{\otimes k}$, with $U$ sampled from a $2k$-design measure, then the corresponding random quantum channel is typically an optimal $k$-copy tensor product expander, a concept introduced by Harrow and Hastings (Quant. Inf. Comput. 2009).