This paper studies the quasi-stationary distributions for a single death process (or downwardly skip-free process) with killing defined on the non-negative integers, corresponding to a non-conservative transition rate matrix. The set $\{1,2,3,\cdots\}$ constitutes an irreducible class and $0$ is an absorbing state. For the single death process with three kinds of killing term, we obtain the existence and uniqueness of the quasi-stationary distribution. Moreover, we derive the conditions for exponential convergence to the quasi-stationary distribution in the total variation norm. Our main approach is based on the Doob's $h$-transform, potential theory and probabilistic methods.