We establish sharp upper and lower bounds of Gaussian type for the heat kernel in the metric measure space satisfying $\RCD(0,N)$ ( equivalently, $\RCD^\ast(0,N)$) condition with $N\in \mathbb{N}\setminus\{1\}$ and having maximum volume growth, and then show its application on the large-time asymptotics of the heat kernel, sharp bounds on the (minimal) Green function, and above all, the large-time asymptotics of the Perelman entropy and the Nash entropy, where for the former the monotonicity of the Perelman entropy is proved. The results generalize the corresponding ones in Riemannian manifolds and also in metric measure spaces obtained recently by the author with R. Jiang and H. Zhang in \cite{JLZ2014}.