We propose two signature-based methods to solve the optimal stopping problem - that is, to price American options - in non-Markovian frameworks. Both methods rely on a global approximation result for $L^p-$functionals on rough path-spaces, using linear functionals of robust, rough path signatures. In the primal formulation, we present a non-Markovian generalization of the famous Longstaff-Schwartz algorithm, using linear functionals of the signature as regression basis. For the dual formulation, we parametrize the space of square-integrable martingales using linear functionals of the signature, and apply a sample average approximation. We prove convergence for both methods and present first numerical examples in non-Markovian and non-semimartingale regimes.