This paper studies the f-ergodicity and its exponential convergence rate for continuous-time Markov chain. Assume f is square integrable, for reversible Markov chain, it is proved that the exponential convergence of f-ergodicity holds if and only if the spectral gap of the generator is positive. Moreover, the convergence rate is equal to the spectral gap. For irreversible case, the positivity of spectral gap remains a sufficient condition of f-ergodicity. The effectiveness of these results are illustrated by some typical examples.