For $r\geq 2$ and $p\geq 1$, the $p$-spectral radius of an $r$-uniform hypergraph $H=(V,E)$ on $n$ vertices is defined to be $$ρ_p(H)=\max_{{\bf x}\in \mathbb{R}^n: \|{\bf x}\|_p=1}r \cdot \!\!\!\! \sum_{\{i_1,i_2,\ldots, i_r\}\in E(H)} x_{i_1}x_{i_2}\cdots x_{i_r},$$ where the maximum is taken over all ${\bf x\in \mathbb{R}^n}$ with the $p$-norm equals 1. In this paper, we proved for any integer $r\geq 2$, and any real $p\geq 1$, and any $r$-uniform hypergraph $H$ with $m={s\choose r}$ edges (for some real $s\geq r-1$), we have $$λ_p(H)\leq \frac{rm}{s^{r/p}}.$$ The equality holds if and only if $s$ is an integer and $H$ is the complete $r$-uniform hypergraph $K^r_s$ with some possible isolated vertices added. Thus, we completely settled a conjecture of Nikiforov. In particular, we settled all the principal cases of the Frankl-Füredi's Conjecture on the Lagrangians of $r$-uniform hypergraphs for all $r\geq 2$.