We provide precise asymptotic estimates for the number of general phylogenetic networks by using analytic combinatorial methods. Recently, this approach is studied by Fuchs, Gittenberger, and the author himself (Australasian Journal of Combinatorics 73(2):385-423, 2019), to count networks with few reticulation vertices for two subclasses: tree-child and normal networks. We follow this line of research to show how to obtain results on the enumeration of general phylogenetic networks.