Let $G(n, r, s)$ be a graph whose vertices are all $r$-element subsets of an $n$-element set, in which two vertices are adjacent if they intersect in exactly $s$ elements. In this paper we study chromatic numbers of $G(n, r, s)$ with $r, s$ being fixed constants and $n$ tending to infinity. Using a recent result of Keevash on existence of designs we deduce an inequality $χ(G(n, r, s)) \le (1+o(1))n^{r-s} \frac{(r-s-1)!}{(2r-2s-1)!}$ for $r > s$ with $r, s$ fixed constants. This inequality gives sharp upper bounds for $r \le 2s+1$. Also we develop an elementary approach to this problem and prove that $χ(G(n, 4, 2)) \sim \frac{n^2}{6}$ without use of Keevash's results. Some bounds on the list chromatic number of $G(n, r, s)$ are also obtained.