Let $G$ be a finite permutation group on $Ω$. An ordered sequence $(ω_1,\ldots,ω_\ell)$ of elements of $Ω$ is an irredundant base for $G$ if the pointwise stabilizer is trivial and no point is fixed by the stabilizer of its predecessors. If all irredundant bases of $G$ have the same cardinality, $G$ is said to be an IBIS group. Lucchini, Morigi and Moscatiello have proved a theorem reducing the problem of classifying finite primitive IBIS groups $G$ to the case that the socle of $G$ is either abelian or non-abelian simple. In this paper, we classify the finite primitive IBIS groups having socle an alternating group. Moreover, we propose a conjecture aiming to give a classification of all almost simple primitive IBIS groups.