We study the action of a differential operator on Schubert polynomials. Using this action, we first give a short new proof of an identity of I. Macdonald (1991). We then prove a determinant conjecture of R. Stanley (2017). This conjecture implies the (strong) Sperner property for the weak order on the symmetric group, a property recently established by C. Gaetz and Y. Gao (2018).