Given an acyclic oriented graph $\vec{H}$ and a graph $G$, we write $G \to \vec{H}$ if every orientation of $G$ has an oriented copy of $\vec{H}$. We define $\vec{R}(\vec{H})$ as the smallest number $n$ such that there exists a graph $G$ satisfying $G \to \vec{H}$. Denoting by $R(H)$ the classical Ramsey number of a graph $H$, we show that $\vec{R}(\vec{H}) \leq 2R(H)^{c \log^2 h}$ for every acyclic oriented graph $\vec{H}$ with $h$ vertices, where $H$ is its underlying undirected graph. We also study the threshold function for the event $\{G(n,p) \to \vec{H}\}$ in the binomial random graph $G(n,p)$. Finally, we consider the isometric case, in which we require that, for every two vertices $x, y \in V(\vec{H})$ and their respective copies $x', y'$ in $\vec{G}$, the distance between $x$ and $y$ is equal to the distance between $x'$ and $y'$. We prove an upper bound for the isometric Ramsey number of an acyclic orientation of the cycle, applying the hypergraph container lemma in random graphs.