The Al-Salam-Chihara polynomials are an important family of orthogonal polynomials in one variable $x$ depending on 3 parameters $α$, $β$ and $q$. They are closely connected to a model from statistical mechanics called the partially asymmetric simple exclusion process (PASEP) and they can be obtained as a specialization of the Askey-Wilson polynomials. We give two different combinatorial formulas for the coefficients of the (transformed) Al-Salam-Chihara polynomials. Our formulas make manifest the fact that the coefficients are polynomials in $α$, $β$ and $q$ with positive coefficients.