We prove that if $σ\in S_m$ is a pattern of $w \in S_n$, then we can express the Schubert polynomial $\mathfrak{S}_w$ as a monomial times $\mathfrak{S}_σ$ (in reindexed variables) plus a polynomial with nonnegative coefficients. This implies that the set of permutations whose Schubert polynomials have all their coefficients equal to either 0 or 1 is closed under pattern containment. Using Magyar's orthodontia, we characterize this class by a list of twelve avoided patterns. We also give other equivalent conditions on $\mathfrak{S}_w$ being zero-one. In this case, the Schubert polynomial $\mathfrak{S}_w$ is equal to the integer point transform of a generalized permutahedron.