We present some results on the proportion of permutations of length $n$ containing certain mesh patterns as $n$ grows large, and give exact enumeration results in some cases. In particular, we focus on mesh patterns where entire rows and columns are shaded. We prove some general results which apply to mesh patterns of any length, and then consider mesh patterns of length four. An important consequence of these results is to show that the proportion of permutations containing a mesh pattern can take a wide range of values between $0$ and $1$.