Using an exhaustive search on cubic graphs of order 16, we find a unique cospectral pair with different chromatic indexes. This example indicates that the chromatic index of a regular graph is not characterized by its spectrum, which answers a question recently posed in [O. Etesami, W. H. Haemers, On NP-hard graph properties characterized by the spectrum, Discrete Appl. Math., 285(2020)526-529]. We prove that any orthogonal matrix representing the similarity between the two adjacency matrices of the cospectral pair cannot be rational. This implies that the cospectral pair cannot be obtained using the original GM-switching method or its generalizations based on rational orthogonal matrices.