Let $X$ and $Y$ be two graphs of order $n$. The friends-and-strangers graph $\textup{FS}(X,Y)$ of $X$ and $Y$ is a graph whose vertex set consists of all bijections $σ: V(X)\rightarrow V(Y)$, in which two bijections $σ$ and $ σ'$ are adjacent if and only if they agree on all but two adjacent vertices of $X$ such that the corresponding images are adjacent in $Y$. The most fundamental question about these friends-and-strangers graphs is whether they are connected. In this paper, we provide a sufficient condition regarding the maximum degree $Δ(X)$ and vertex connectivity $κ(Y)$ that ensures the graph $\textup{FS}(X,Y)$ is $s$-connected. As a corollary, we improve upon a result by Bangachev and partially confirm a conjecture he proposed. Furthermore, we completely characterize the connectedness of $\textup{FS}(X,Y)$, where $X\in\textup{DL}_{n-k,k}$.