It is a standard result that the Hankel determinants for a sequence stay invariant after performing the binomial transform on this sequence. In this work, we extend the scenario to $q$-binomial transforms and study the behavior of the leading coefficient in such Hankel determinants. We also investigate the leading coefficient in the Hankel determinants for even-indexed Bernoulli polynomials with recourse to a curious binomial transform. In particular, the degrees of these Hankel determinants share the same nature as those in one of the $q$-binomial cases.