A set of Pauli stings is well characterized by the graph that encodes its commutatitivity structure, i.e., by its frustration graph. This graph provides a natural interface between graph theory and quantum information, which we explore in this work. We investigate all aspects of this interface for a special class of graphs that bears tight connections between the groundstate structures of a spin systems and topological structure of a graph. We call this class $\hbar$-perfect, as it extends the class of perfect and $h$-perfect graphs. Having an $\hbar$-perfect graph opens up several applications: we find efficient schemes for entanglement detection, a connection to the complexity of shadow tomography, tight uncertainty relations and a construction for computing good lower on bounds ground state energies. Conversely this also induces quantum algorithms for computing the independence number. Albeit those algorithms do not immediately promise an advantage in runtime, we show that an approximate Hamilton encoding of the independence number can be achieved with an amount of qubits that typically scales logarithmically in the number of vertices. We also we also determine the behavior of $\hbar$-perfectness under basic graph operations and evaluate their prevalence among all graphs.