The generic anisotropy is an important property in the study of Stanley-Reisner rings of homology spheres, which was introduced by Papadakis and Petrotou. This property can be used to prove the strong Lefschetz property as well as McMullen's $g$-conjecture for homology spheres. It is conjectured that for an arbitrary field $\mathbb{F}$, any $\mathbb{F}$-homology sphere is generically anisotropic over $\mathbb{F}$. In this paper, we prove this conjecture for all strongly edge decomposable spheres.