We show how multiplicatively syndetic sets can be used in the study of partition regularity of dilation invariant systems of polynomial equations. In particular, we prove that a dilation invariant system of polynomial equations is partition regular if and only if it has a solution inside every multiplicatively syndetic set. We also adapt the methods of Green-Tao and Chow-Lindqvist-Prendiville to develop a syndetic version of Roth's density increment strategy. This argument is then used to obtain bounds on the Rado numbers of configurations of the form $\{x, d, x + d, x + 2d\}$.