We develop the theory of torsional rigidity -- a quantity routinely considered for Dirichlet Laplacians on bounded planar domains -- for Laplacians on metric graphs with at least one Dirichlet vertex. Using a variational characterization that goes back to Pólya, we develop surgical principles that, in turn, allow us to prove isoperimetric-type inequalities: we can hence compare the torsional rigidity of general metric graphs with that of intervals of the same total length. In the spirit of the Kohler-Jobin Inequality, we also derive sharp bounds on the ground-state energy of a quantum graph in terms of its torsional rigidity: this is particularly attractive since computing the torsional rigidity reduces to inverting a matrix whose size is the number of the graph's vertices and is, thus, much easier than computing eigenvalues.