In this paper, we mainly establish a congruence for a sum involving Apéry numbers, which was conjectured by Z.-W. Sun. Namely, for any prime $p>3$ and positive odd integer $m$, we prove that there is a $p$-adic integer $c_m$ only depending on $m$ such that $$\sum_{k=0}^{p-1}(2k+1)^{m}(-1)^kA_k\equiv c_mp\left(\frac{p}{3}\right)\pmod{p^3},$$ where $A_k=\sum_{j=0}^{k}\binom{k}{j}^2\binom{k+j}{j}^2$ is the Apéry number and $(\frac{\cdot}{p})$ is the Legendre symbol.