In this paper, we introduce the concept of a relative Heffter space which simultaneously generalizes those of relative Heffter arrays and Heffter spaces. Given a subgroup $J$ of an abelian group $G$, a relative Heffter space is a resolvable configuration whose points form a half-set of $G\setminus{J}$ and whose blocks are all zero-sum in $G$. Here we present two infinite families of relative Heffter spaces satisfying the additional condition of being simple. As a consequence, we get new results on globally simple relative Heffter arrays, on mutually orthogonal cycle decompositions and on biembeddings of cyclic cycle decompositions of the complete multipartite graph into an orientable surface.