We introduce differential games for FO logic of graphs, a variant of Ehrenfeucht-Fraïssé games in which the game is played on only one graph and the moves of both players restricted. We prove that, in a certain sense, these games are strong enough to capture essential information about graphs from graph classes which are interpretable in nowhere dense graph classes. This, together with the newly introduced notion of differential locality and the fact that the restriction of possible moves by the players makes it easy to decide the winner of the game in some cases, leads to a new approach to the FO model checking problem on interpretations of nowhere dense graph classes.