A step forward is made in a long standing Lovász's problem regarding hamiltonicity of vertex-transitive graphs by showing that every connected vertex-transitive graph of order a product of two primes, other than the Petersen graph, contains a Hamilton cycle. Essential tools used in the proof range from classical results on existence of Hamilton cycles, such as Chvátal's theorem and Jackson's theorem, to certain results on polynomial representations of quadratic residues at primitive roots in finite fields.