Let G be a simple connected graph. Then chi L(G) and chi D(G) will denote the locating chromatic number and the distinguishing chromatic number of G, respectively. In this paper, we investigate a comparison between chi L(G) and chi D(G). In fact, we prove that chi D(G) \leq chi L(G). Moreover, we determine some types of graphs whose locating and distinguishing chromatic numbers are equal. Specially, we characteristic all graph G with the property that chi D(G)= chi L(G) = 3.