Jacob Fox, C. Seshadhri, Tim Roughgarden, Fan Wei, and Nicole Wein introduced the model of $c$-closed graphs--a distribution-free model motivated by triadic closure, one of the most pervasive structural signatures of social networks. While enumerating maximal cliques in general graphs can take exponential time, it is known that in $c$-closed graphs, maximal cliques and maximal complete bipartite subgraphs can always be enumerated in polynomial time. These structures correspond to blow-ups of simple patterns: a single vertex or a single edge, with some vertices required to form cliques. In this work, we explore a natural extension: we study maximal blow-ups of arbitrary finite graphs $H$ in $c$-closed graphs. We prove that for any fixed graph $H$, the number of maximal blow-ups of $H$ in an $n$-vertex $c$-closed graph is always bounded by a polynomial in $n$. We further investigate the case of induced blow-ups and provide a precise characterization of the graphs $H$ for which the number of maximal induced blow-ups is also polynomially bounded in $n$. Finally, we study the analogue questions when $H$ ranges over an infinite family of graphs.