We present combinatorial and analytical results concerning a Sheffer sequence with an exponential generating function of the form $G(s,z)=e^{czs+αz^{2}+βz^{4}}$, where $α, β, c \in \mathbb{R}$ with $β<0$ and $c\neq 0$. We demonstrate that the zeros of all polynomials in such a Sheffer sequence are either real, or purely imaginary. Additionally, using the properties of Riordan matrices we show that our Sheffer sequence satisfies a three-term recurrence relation of order 4, and we also exhibit a connection between the coefficients of these Sheffer polynomials and the number of nodes with a a given label in certain marked generating trees.