In this paper, we study the $2$-binomial complexity $b_{\mathbf{t}_{m},2}(n)$ of the generalized Thue-Morse words $\mathbf{t}_{m}$ for every integer $m\geq 3$. We obtain the exact value of $b_{\mathbf{t}_{m},2}(n)$ for every integer $n\geq m^{2}$. As a consequence, $b_{\mathbf{t}_{m},2}(n)$ is ultimately periodic with period $m^{2}$. This result partially answers a question of M. Lejeune, J. Leroy and M. Rigo [Computing the $k$-binomial complexity of the Thue-Morse word, J. Comb. Theory Ser. A, {\bf 176} (2020) 105284].