Let $G$ be a graph on $n$ vertices and $λ_1,λ_2,\ldots,λ_n$ its eigenvalues. The Estrada index of $G$ is an invariant that is calculated from the eigenvalues of the adjacency matrix of a graph. In this paper, we present some new lower bounds obtained for the Estrada Index of graphs and in particular of bipartite graphs that only depend on the number of vertices, the number of edges, Randić index, maximum and minimum degree and diameter.