A graph class is monotone if it is closed under taking subgraphs. It is known that a monotone class defined by finitely many obstructions has bounded treewidth if and only if one of the obstructions is a so-called tripod, that is, a disjoint union of trees with exactly one vertex of degree 3 and paths. This dichotomy also characterizes exactly those monotone graph classes for which many NP-hard algorithmic problems admit polynomial-time algorithms. These algorithmic dichotomies, however, do not extend to the universe of all hereditary classes, which are classes closed under taking induced subgraphs. This leads to the natural question of whether we can extend known algorithmic dichotomies for monotone classes to larger families of hereditary classes. We give an affirmative answer to this question by considering the family of hereditary graph classes that are closed under self-intersection, which is known to be located strictly between the monotone and hereditary classes. We prove a new structural characterization of graphs in self-intersection-closed classes excluding a tripod. We use our characterization to give a complete dichotomy of Maximum Independent Set, and its weighted variant for self-intersection-closed classes defined by finitely many obstructions: these problems are in P if the class excludes a tripod and NP-hard otherwise. This generalizes several known results on Maximum Independent Set. We also use it to obtain dichotomies for Maximum Induced Matching on self-intersection-closed classes of bipartite graphs defined by finitely many obstructions. Similarly, we obtain dichotomies for Satisfiability and Counting Satisfiability on self-intersection-closed classes of (bipartite) incidence graphs defined by finitely many obstructions, and for boundedness of clique-width for self-intersection-closed classes of bipartite graphs defined by finitely many obstructions.