Hand gesture recognition based on surface electromyographic (sEMG) signals is a promising approach for developing Human-Machine Interfaces (HMIs) with a natural control, such as intuitive robot interfaces or poly-articulated prostheses. However, real-world applications are limited by reliability problems due to motion artefacts, postural and temporal variability, and sensor re-positioning. This master thesis is the first application of deep learning on the Unibo-INAIL dataset, the first public sEMG dataset exploring the variability between subjects, sessions and arm postures by collecting data over 8 sessions of each of 7 able-bodied subjects executing 6 hand gestures in 4 arm postures. Recent studies address variability with strategies based on training set composition, which improve inter-posture and inter-day generalization of non-deep machine learning classifiers, among which the RBF-kernel SVM yields the highest accuracy. The deep architecture realized in this work is a 1d-CNN inspired by a 2d-CNN reported to perform well on other public benchmark databases. On this 1d-CNN, various training strategies based on training set composition were implemented and tested. Multi-session training proves to yield higher inter-session validation accuracies than single-session training. Two-posture training proves the best postural training (proving the benefit of training on more than one posture) and yields 81.2% inter-posture test accuracy. Five-day training proves the best multi-day training, yielding 75.9% inter-day test accuracy. All results are close to the baseline. Moreover, the results of multi-day training highlight the phenomenon of user adaptation, indicating that training should also prioritize recent data. Though not better than the baseline, the achieved classification accuracies rightfully place the 1d-CNN among the candidates for further research.