Supervised learning with large-scale data usually leads to complex optimization problems, especially for classification tasks with multiple classes. Stochastic subgradient methods can enable efficient learning with a large number of samples for classification techniques that minimize the average loss over the training samples. However, recent techniques, such as minimax risk classifiers (MRCs), minimize the maximum expected loss and are not amenable to stochastic subgradient methods. In this paper, we present a learning algorithm based on the combination of constraint and column generation that enables efficient learning of MRCs with large-scale data for classification tasks with multiple classes. Experiments on multiple benchmark datasets show that the proposed algorithm provides upto a 10x speedup for general large-scale data and around a 100x speedup with a sizeable number of classes.