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stat.ML updates on arXiv.org

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Two-step interpretable modeling of Intensive Care Acquire...
Giacomo Lancia, Meri Varkila, Olaf Cremer, Cristian Spitoni · 2023-01-26 · via stat.ML updates on arXiv.org

We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining interpretability of the models. To go beyond the black box paradigm of artificial neural networks, we propose a parsimonious and robust semi-parametric approach (i.e., a landmarking competing risks model) that combines routinely collected low-resolution data with predictive features extracted from a convolutional neural network, that was trained on high resolution time-dependent information. We then use saliency maps to analyze and explain the extra predictive power of this model. To illustrate our methodology, we focus on healthcare-associated infections in patients admitted to an intensive care unit.