Current data-driven traffic prediction models are usually trained with large datasets, e.g. several months of speeds and flows. Such models provide very good fit for ordinary road conditions, but often fail just when they are most needed: when traffic suffers a sudden and significant disruption, such as a road incident. In this work, we describe QTIP: a simulation-based framework for quasi-instantaneous adaptation of prediction models upon traffic disruption. In a nutshell, QTIP performs real-time simulations of the affected road for multiple scenarios, analyzes the results, and suggests a change to an ordinary prediction model accordingly. QTIP constructs the simulated scenarios per properties of the incident, as conveyed by immediate distress signals from affected vehicles. Such real-time signals are provided by In-Vehicle Monitor Systems, which are becoming increasingly prevalent world-wide. We experiment QTIP in a case study of a Danish motorway, and the results show that QTIP can improve traffic prediction in the first critical minutes of road incidents.