Decoding neurons to extract information from transmission and employ them into other use is the goal of neuroscientists' study. Due to that the field of neuroscience is utilizing the traditional methods presently, we hence combine the state-of-the-art deep learning techniques with the theory of neuron decoding to discuss its potential of accomplishment. Besides, the stress level that is related to neuron activity in hippocampus is statistically examined as well. The experiments suggest that our state-of-the-art deep learning-based stress determinator provides good performance with respect to its model prediction accuracy and additionally, there is strong evidence against equivalence of mouse stress level under diverse environments.