We investigate a multi-agent model of firms in an R\&D network. Each firm is characterized by its knowledge stock $x_{i}(t)$, which follows a non-linear dynamics. It can grow with the input from other firms, i.e., by knowledge transfer, and decays otherwise. Maintaining interactions is costly. Firms can leave the network if their expected knowledge growth is not realized, which may cause other firms to also leave the network. The paper discusses two bottom-up intervention scenarios to prevent, reduce, or delay cascades of firms leaving. The first one is based on the formalism of network controllability, in which driver nodes are identified and subsequently incentivized, by reducing their costs. The second one combines node interventions and network interventions. It proposes the controlled removal of a single firm and the random replacement of firms leaving. This allows to generate small cascades, which prevents the occurrence of large cascades. We find that both approaches successfully mitigate cascades and thus improve the resilience of the R\&D network.