The minimum dominating set (MDS) problem is a fundamental subject of theoretical computer science, and has found vast applications in different areas, including sensor networks, protein interaction networks, and structural controllability. However, the determination of the size of a MDS and the number of all MDSs in a general network is NP-hard, and it thus makes sense to seek particular graphs for which the MDS problem can be solved analytically. In this paper, we study the MDS problem in the pseudofractal scale-free web and the Sierpiński graph, which have the same number of vertices and edges. For both networks, we determine explicitly the domination number, as well as the number of distinct MDSs. We show that the pseudofractal scale-free web has a unique MDS, and its domination number is only half of that for the Sierpiński graph, which has many MDSs. We argue that the scale-free topology is responsible for the difference of the size and number of MDSs between the two studied graphs, which in turn indicates that power-law degree distribution plays an important role in the MDS problem and its applications in scale-free networks.